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About BMC Bioinformatics - Latest articles


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BMC Bioinformatics - Latest articles has written 3 articles so far, you can find them below.


Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm

Conclusions: The GA-based CTPP primer design method provides all forms of estimation for the common primer constraints of PCR-CTPP. The GA-CTPP program is implemented in JAVA and a user-friendly input interface is freely available at http://bio.kuas.edu.tw/ga-ctpp/. (Source: BMC Bioinformatics - Latest articles)

SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping

RFLP variation by VNTR loss.
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Conclusions: The user interfaces for functional SNP analyses have been substantially improved and integrated. SNP-RFLPing 2 offers a new and user-friendly interface for RFLP genotyping that can be used in association studies and is freely available at http://bio.kuas.edu.tw/snp-rflping2. (Source: BMC Bioinformatics - Latest articles)
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Linked region detection using high-density SNP genotype data via the minimum recombinant model of pedigree haplotype inference

Conclusions: Our new package (LIden) is efficient software for linked region detection using high-density SNPgenotype data. LIden can handle some important cases where the existing programs do not work well. Inparticular, the new package can handle many cases where the genotype data of one of the two parents is missingfor the entire chromosome. The running time of the program is O(mn), where m is the number of members inthe family and n is the number of SNP sites in the chromosome. LIden is specifically suitable for handling bigsized families. This research also demonstrates another practical use of the minimum recombinant model forhaplotype inference in pedigrees.The software package can be downloaded at http://www.cs.cityu.edu.hk/~lwang/software/Link. (Source: BMC Bioinformatics - Latest...

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